Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 5/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.48 |
| ▸ | EPAS1 | Q99814 | 6/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD5 | P21918 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29086568 | 0.87 | CHRNB2 (0.53) | KDM1ACHRNB2CHRNA4EPAS1POLB | |
| SCHEMBL2527089 | 0.87 | CHRNB2 (0.53) | KDM1ACHRNB2CHRNA4EPAS1POLB | |
| SCHEMBL29964556 | 0.87 | CHRNB2 (0.53) | KDM1ACHRNB2CHRNA4EPAS1POLB | |
| SCHEMBL29884098 | 0.87 | CHRNB2 (0.53) | KDM1ACHRNB2CHRNA4EPAS1POLB | |
| SCHEMBL30551214 | 0.85 | MEN1 (0.54) | KDM1ACHRNB2CHRNA4EPAS1POLB | |
| SCHEMBL29331199 | 0.85 | MEN1 (0.54) | KDM1ACHRNB2CHRNA4EPAS1POLB | |
| SCHEMBL15447576 | 0.85 | MEN1 (0.54) | KDM1ACHRNB2CHRNA4EPAS1POLB | |
| Hydrochloric Acid SCHEMBL3725483 | 0.85 | CHRNB2 (0.51) | KDM1ACHRNB2CHRNA4EPAS1POLB | |
| Hydrochloric Acid SCHEMBL22498444 | 0.85 | CHRNB2 (0.51) | KDM1ACHRNB2CHRNA4EPAS1POLB | |
| SCHEMBL27645268 | 0.80 | KDM1A (0.42) | KDM1AEPAS1POLBHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107108492-A | Inhibitor of cellular necrosis | 北京生命科学研究所 | 2017-08-29 | — | — | CN | disclosed |