Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.54 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.54 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | KDM1A | O60341 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD5 | P21918 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15447576 | 1.00 | MEN1 (0.54) | MEN1KMT2ACYP2D6CYP2C19CHRNB2 | |
| SCHEMBL30551214 | 1.00 | MEN1 (0.54) | MEN1KMT2ACYP2D6CYP2C19CHRNB2 | |
| SCHEMBL29086568 | 0.95 | CHRNB2 (0.53) | MEN1KMT2ACYP2D6CYP2C19CHRNB2 | |
| SCHEMBL29964556 | 0.95 | CHRNB2 (0.53) | MEN1KMT2ACYP2D6CYP2C19CHRNB2 | |
| SCHEMBL29884098 | 0.95 | CHRNB2 (0.53) | MEN1KMT2ACYP2D6CYP2C19CHRNB2 | |
| SCHEMBL2527089 | 0.95 | CHRNB2 (0.53) | MEN1KMT2ACYP2D6CYP2C19CHRNB2 | |
| Hydrochloric Acid SCHEMBL22498444 | 0.93 | CHRNB2 (0.51) | MEN1KMT2ACYP2D6CYP2C19CHRNB2 | |
| Hydrochloric Acid SCHEMBL3725483 | 0.93 | CHRNB2 (0.51) | MEN1KMT2ACYP2D6CYP2C19CHRNB2 | |
| SCHEMBL28848937 | 0.85 | KDM1A (0.48) | MEN1KMT2ACHRNB2CHRNA4POLB | |
| SCHEMBL468999 | 0.79 | MEN1 (0.54) | MEN1KMT2ACYP2D6CYP2C19CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240228478-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. | 2024-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240228478-A1 | COMPOUNDS AND METHODS OF USE | F12, C1R, ABCG2 | MEN1 142/4885KMT2A 4008/4885CYP2D6 33/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.