1,6-Hexanediol

1,6-Hexanediol

SCHEMBL28848979

C=CC(=O)O.C=CC(=O)OC.OCCCCCCO

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.42
ALDH1A1 P00352 5/20 0.42
CYP3A4 P08684 2/20 0.42
LMNA P02545 2/20 0.40
HCAR2 Q8TDS4 2/20 0.40
HPGD P15428 1/20 0.38
GPR84 Q9NQS5 1/20 0.37
FFAR1 O14842 1/20 0.37
FFAR4 Q5NUL3 1/20 0.37
HSD17B10 Q99714 2/20 0.36
ALOX15 P16050 1/20 0.36
CYP4F2 P78329 2/20 0.36
CYP4A11 Q02928 2/20 0.36
KEAP1 Q14145 1/20 0.36
NFE2L2 Q16236 1/20 0.36
TP53 P04637 3/20 0.34
HIF1A Q16665 3/20 0.34
MAPK1 P28482 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid Methyl Ester SCHEMBL28029883 0.94 TSHR (0.46) TSHRALDH1A1CYP3A4LMNAHCAR2
1,6-Hexanediol SCHEMBL27393515 0.94 TSHR (0.46) TSHRALDH1A1CYP3A4LMNAHCAR2
Acrylic Acid Methyl Ester SCHEMBL28826944 0.94 TSHR (0.46) TSHRALDH1A1CYP3A4LMNAHCAR2
1,6-Hexanediol SCHEMBL10634052 0.94 TSHR (0.46) TSHRALDH1A1CYP3A4LMNAHCAR2
Acrylic Acid Methyl Ester SCHEMBL27334995 0.92 TSHR (0.48) TSHRALDH1A1CYP3A4LMNAHCAR2
Acrylic Acid Methyl Ester SCHEMBL27461506 0.90 TSHR (0.46) TSHRALDH1A1CYP3A4LMNAHCAR2
1,6-Hexanediol SCHEMBL9406796 0.87 LMNA (0.48) TSHRALDH1A1CYP3A4LMNAHPGD
Acrylic Acid Methyl Ester SCHEMBL6680386 0.87 TSHR (0.48) TSHRALDH1A1CYP3A4LMNAHCAR2
Adipic Acid SCHEMBL28172406 0.87 GPR84 (0.57) TSHRALDH1A1LMNAGPR84FFAR1
Cetyl Alcohol SCHEMBL27907915 0.86 TSHR (0.50) TSHRALDH1A1CYP3A4LMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105339448-B The coating composition of the Michael-adduct containing polysiloxane 3M创新有限公司 2017-11-03 CN disclosed