Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 6/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | LIPE | Q05469 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3841236 | 0.81 | ROCK2 (0.46) | ROCK2CA12CA1CA2CA9 | |
| SCHEMBL28806018 | 0.74 | ROCK2 (0.46) | ROCK2CA12CA1CA2CA9 | |
| SCHEMBL28849120 | 0.74 | ROCK2 (0.46) | ROCK2CA12CA1CA2CA9 | |
| SCHEMBL27470019 | 0.74 | ROCK2 (0.46) | ROCK2CA12CA1CA2CA9 | |
| SCHEMBL28849106 | 0.73 | DDB1 (0.49) | ROCK2CA12CA1CA2CA9 | |
| SCHEMBL28849019 | 0.72 | PDE4A (0.46) | CA12CA1CA2CA9DDB1 | |
| SCHEMBL7576221 | 0.72 | ROCK2 (0.44) | ROCK2CA12CA1CA2CA9 | |
| SCHEMBL8427476 | 0.72 | HTT (0.47) | ROCK2CA12CA1CA2CA9 | |
| SCHEMBL15552907 | 0.71 | DDB1 (0.56) | ROCK2CA12CA1CA2CA9 | |
| SCHEMBL5872162 | 0.71 | MEN1 (0.42) | ROCK2ALDH1A1MAPTHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108069952-B | Quinolinone compound and application thereof in medicines | 广东东阳光药业有限公司 | 2022-09-27 | — | — | CN | disclosed |