Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9433304 | 0.84 | POLB (0.49) | PDE4APDE4BPDE4CPDE4DNPC1 | |
| SCHEMBL7456282 | 0.80 | PDE4A (0.50) | PDE4APDE4BPDE4CPDE4DNPC1 | |
| SCHEMBL31716545 | 0.75 | BRD4 (0.58) | PDE4APDE4BPDE4CPDE4DNPC1 | |
| SCHEMBL2152756 | 0.74 | BPTF (0.61) | PDE4APDE4BPDE4CPDE4DNPC1 | |
| SCHEMBL4105055 | 0.74 | POLB (0.51) | PDE4APDE4BPDE4CPDE4DNPC1 | |
| SCHEMBL28849021 | 0.73 | NPC1 (0.45) | PDE4APDE4BPDE4CPDE4DNPC1 | |
| SCHEMBL12974281 | 0.72 | ALDH1A1 (0.53) | ALDH1A1MAPTSMN1; SMN2TP53HTT | |
| SCHEMBL5105230 | 0.72 | GRM2 (0.56) | PDE4APDE4BPDE4CPDE4DNPC1 | |
| SCHEMBL28849104 | 0.72 | ROCK2 (0.43) | NPC1CA12CA1CA2CA9 | |
| SCHEMBL892079 | 0.70 | ALDH1A1 (0.67) | NPC1CA12CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108069952-B | Quinolinone compound and application thereof in medicines | 广东东阳光药业有限公司 | 2022-09-27 | — | — | CN | disclosed |