Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 8/20 | 0.62 |
| ▸ | GNAI3 | P08754 | 9/20 | 0.59 |
| ▸ | GNAI1 | P63096 | 9/20 | 0.59 |
| ▸ | GNAO1 | P09471 | 8/20 | 0.59 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27799378 | 0.88 | EPHX2 (0.60) | EPHX2GNAI3GNAI1GNAO1EPHX1 | |
| SCHEMBL11928134 | 0.88 | GNAI3 (0.59) | EPHX2GNAI3GNAI1GNAO1EPHX1 | |
| SCHEMBL15759096 | 0.83 | GNAI3 (0.53) | EPHX2GNAI3GNAI1GNAO1EPHX1 | |
| SCHEMBL24330250 | 0.81 | EPHX2 (0.55) | EPHX2GNAI3GNAI1GNAO1EPHX1 | |
| SCHEMBL27778381 | 0.80 | EPHX2 (0.86) | EPHX2EPHX1 | |
| SCHEMBL25122003 | 0.79 | L3MBTL1 (0.51) | EPHX2GNAI3GNAI1GNAO1EPHX1 | |
| SCHEMBL25122006 | 0.78 | GNAI3 (0.52) | EPHX2GNAI3GNAI1GNAO1L3MBTL1 | |
| SCHEMBL25853853 | 0.78 | GNAI3 (0.52) | EPHX2GNAI3GNAI1GNAO1L3MBTL1 | |
| SCHEMBL7490420 | 0.78 | GNAI3 (0.68) | GNAI3GNAI1GNAO1L3MBTL1MEN1 | |
| SCHEMBL25934640 | 0.78 | NPC1 (0.79) | GNAI3GNAI1GNAO1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107098871-A | Phenylpropionyl amine derivant, its preparation method and its in application pharmaceutically | 江苏恒瑞医药股份有限公司 | 2017-08-29 | — | — | CN | disclosed |