Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 3/20 | 0.42 |
| ▸ | CES2 | O00748 | 3/20 | 0.41 |
| ▸ | CES1 | P23141 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.39 |
| ▸ | PPARG | P37231 | 6/20 | 0.39 |
| ▸ | PPARD | Q03181 | 6/20 | 0.39 |
| ▸ | PPARA | Q07869 | 6/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TLR2 | O60603 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31079557 | 1.00 | DNM1 (0.42) | DNM1CES2CES1MEN1KMT2A | |
| SCHEMBL28059469 | 1.00 | DNM1 (0.42) | DNM1CES2CES1MEN1KMT2A | |
| SCHEMBL18641846 | 1.00 | DNM1 (0.42) | DNM1CES2CES1MEN1KMT2A | |
| SCHEMBL29112735 | 1.00 | DNM1 (0.42) | DNM1CES2CES1MEN1KMT2A | |
| SCHEMBL31079440 | 1.00 | DNM1 (0.42) | DNM1CES2CES1MEN1KMT2A | |
| SCHEMBL1395513 | 0.98 | CES2 (0.39) | DNM1CES2CES1MEN1KMT2A | |
| SCHEMBL20362237 | 0.91 | — | — | |
| SCHEMBL28091762 | 0.88 | — | — | |
| SCHEMBL27405060 | 0.88 | — | — | |
| SCHEMBL27470543 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107106524-A | Methods for treating protozoal infections | 尼奥酷里私人有限公司 | 2017-08-29 | — | — | CN | claimed |