Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | FPR3 | P25089 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28849438 | 0.90 | MAPT (0.42) | MAPTKMT2ATRPA1HPGDRECQL | |
| SCHEMBL28849430 | 0.88 | MAPT (0.39) | MAPTKMT2ATRPA1HPGDRECQL | |
| SCHEMBL28849431 | 0.88 | TRPA1 (0.41) | MAPTKMT2ATRPA1HPGDRECQL | |
| SCHEMBL28849440 | 0.88 | TRPA1 (0.48) | MAPTKMT2ATRPA1HPGDRECQL | |
| SCHEMBL28849436 | 0.85 | SLC6A4 (0.47) | KMT2ASLC6A2SLC6A4OPRM1MEN1 | |
| SCHEMBL28849415 | 0.83 | SLC6A4 (0.42) | KMT2ASLC6A2SLC6A4OPRM1MEN1 | |
| SCHEMBL28849449 | 0.80 | SLC6A4 (0.44) | MAPTKMT2ATRPA1SLC6A2SLC6A4 | |
| SCHEMBL29950582 | 0.80 | SLC6A2 (0.46) | MAPTKMT2ATRPA1SLC6A2SLC6A4 | |
| SCHEMBL29950355 | 0.80 | SLC6A2 (0.44) | MAPTKMT2ATRPA1HPGDSLC6A2 | |
| SCHEMBL28849429 | 0.80 | SLC6A2 (0.46) | MAPTKMT2ATRPA1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115108875-B | Nitrogen-containing heteroarene chiral cyclic alcohol constructed by asymmetric catalysis of visible light, and preparation method and application thereof | 河南师范大学 | 2023-07-04 | — | — | CN | disclosed |
| CN-115108875-A | Nitrogen-containing heteroarene chiral cyclic alcohol constructed by visible light asymmetric catalysis, and preparation method and application thereof | 河南师范大学 | 2022-09-27 | — | — | CN | disclosed |