Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.39 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | FPR3 | P25089 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28849438 | 0.90 | MAPT (0.42) | TRPA1MAPTOPRM1CNR2HPGD | |
| SCHEMBL28849431 | 0.88 | TRPA1 (0.41) | TRPA1RAB9AMAPTOPRM1OPRL1 | |
| SCHEMBL28849437 | 0.88 | MAPT (0.39) | TRPA1MAPTOPRM1HPGDRECQL | |
| SCHEMBL28849430 | 0.88 | MAPT (0.39) | TRPA1MAPTOPRM1SLC6A9SLC6A5 | |
| SCHEMBL29950460 | 0.87 | SLC6A4 (0.44) | TRPA1RAB9AMAPTOPRM1OPRL1 | |
| SCHEMBL28849449 | 0.87 | SLC6A4 (0.44) | TRPA1RAB9AMAPTOPRM1OPRL1 | |
| SCHEMBL28849436 | 0.85 | SLC6A4 (0.47) | NPC1RAB9AOPRM1OPRL1SLC6A9 | |
| SCHEMBL28849415 | 0.83 | SLC6A4 (0.42) | OPRM1MEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL29950538 | 0.83 | TRPA1 (0.63) | TRPA1OPRM1CNR2MEN1KMT2A | |
| SCHEMBL28849442 | 0.83 | TRPA1 (0.63) | TRPA1OPRM1CNR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115108875-B | Nitrogen-containing heteroarene chiral cyclic alcohol constructed by asymmetric catalysis of visible light, and preparation method and application thereof | 河南师范大学 | 2023-07-04 | — | — | CN | disclosed |
| CN-115108875-A | Nitrogen-containing heteroarene chiral cyclic alcohol constructed by visible light asymmetric catalysis, and preparation method and application thereof | 河南师范大学 | 2022-09-27 | — | — | CN | disclosed |