Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.54 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.54 |
| ▸ | CYP4Z1 | Q86W10 | 2/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.40 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27407292 | 0.89 | CYP4F2 (0.54) | CYP4F2CYP4A11CYP4Z1PDE3BPDE3A | |
| SCHEMBL7522054 | 0.87 | CYP4F2 (0.59) | CYP4F2CYP4A11CYP4Z1PDE3BPDE3A | |
| SCHEMBL5361143 | 0.86 | TLR7 (0.42) | CYP4F2CYP4A11CYP4Z1CYP1A2DPP4 | |
| SCHEMBL6913578 | 0.84 | CYP4F2 (0.61) | CYP4F2CYP4A11CYP4Z1PDE3BPDE3A | |
| Hydrochloric Acid SCHEMBL27571914 | 0.83 | CYP4F2 (0.54) | CYP4F2CYP4A11CYP4Z1PDE3BPDE3A | |
| SCHEMBL11247614 | 0.83 | CYP4F2 (0.56) | CYP4F2CYP4A11CYP4Z1PDE3BPDE3A | |
| SCHEMBL8257852 | 0.82 | CYP4F2 (0.59) | CYP4F2CYP4A11CYP4Z1PDE3BPDE3A | |
| SCHEMBL27989066 | 0.82 | CYP4F2 (0.49) | CYP4F2CYP4A11CYP4Z1PDE3BPDE3A | |
| SCHEMBL25118388 | 0.82 | CYP4F2 (0.55) | CYP4F2CYP4A11CYP4Z1PDE3BPDE3A | |
| SCHEMBL3499415 | 0.82 | CYP4F2 (0.56) | CYP4F2CYP4A11CYP4Z1PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107108593-A | Substituted oxazole and thiazole-based carboxamide and urea derivatives as vanilloid receptor ligands II | 美迪福伦DBT有限公司 | 2017-08-29 | — | — | CN | disclosed |