Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 5/20 | 0.56 |
| ▸ | CYP4A11 | Q02928 | 5/20 | 0.56 |
| ▸ | RXRG | P48443 | 1/20 | 0.42 |
| ▸ | CYP4Z1 | Q86W10 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.40 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7522054 | 0.89 | CYP4F2 (0.59) | CYP4F2CYP4A11CYP4Z1ALDH1A1GAA | |
| SCHEMBL16188852 | 0.87 | CYP4F2 (0.50) | CYP4F2CYP4A11RXRGCYP4Z1ALDH1A1 | |
| SCHEMBL27989066 | 0.86 | CYP4F2 (0.49) | CYP4F2CYP4A11RXRGCYP4Z1ALDH1A1 | |
| SCHEMBL26307337 | 0.85 | CYP4F2 (0.63) | CYP4F2CYP4A11CYP4Z1ALDH1A1GAA | |
| SCHEMBL17748493 | 0.85 | CYP4F2 (0.48) | CYP4F2CYP4A11RXRGCYP4Z1ALDH1A1 | |
| SCHEMBL3906109 | 0.84 | CYP4F2 (0.53) | CYP4F2CYP4A11ALDH1A1GAAPKM | |
| SCHEMBL435614 | 0.82 | CHRNA7 (0.55) | CYP4F2CYP4A11ALDH1A1GAA | |
| SCHEMBL146903 | 0.82 | CYP4F2 (0.55) | CYP4F2CYP4A11CYP4Z1ALDH1A1GAA | |
| SCHEMBL30434824 | 0.82 | CYP4F2 (0.55) | CYP4F2CYP4A11CYP4Z1ALDH1A1GAA | |
| SCHEMBL28849656 | 0.82 | CYP4F2 (0.54) | CYP4F2CYP4A11CYP4Z1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014169817-A1 | PHENYLALANINE COMPOUND HAVING NITROGEN HETEROCYCLIC LINK, PHARMACEUTICAL COMPOSITION THEREOF, PREPARATION METHOD THEREFOR, AND USE THEREOF | 中国科学院上海药物研究所 (CN) | 2014-10-23 | — | — | WO | disclosed |
| US-20100152165-A1 | CARBOXYLIC ACID DERIVATIVES | ASTELLAS PHARMA INC. (JP) | 2010-06-17 | — | — | US | disclosed |
| US-20100152165-A1 | CARBOXYLIC ACID DERIVATIVES | ASTELLAS PHARMA INC. (JP) | 2010-06-17 | — | — | US | disclosed |
| US-20100152165-A1 | CARBOXYLIC ACID DERIVATIVES | ASTELLAS PHARMA INC. (JP) | 2010-06-17 | — | — | US | disclosed |
| EP-2096109-A1 | CARBOXYLIC ACID DERIVATIVE | Astellas Pharma Inc. (JP) | 2009-09-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152165-A1 | CARBOXYLIC ACID DERIVATIVES | GPR119, GPR65, HCAR1 | CYP4F2 2033/4885CYP4A11 588/4885RXRG 541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.