SCHEMBL28850422

SCHEMBL28850422

CN1C(=O)[C@](C)(CC(=O)O)c2ccccc21

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.52
MAPT P10636 4/20 0.52
PKM P14618 1/20 0.52
RAD52 P43351 1/20 0.48
RAB9A P51151 2/20 0.47
HPGD P15428 1/20 0.47
MAPK1 P28482 3/20 0.46
CBX7 O95931 2/20 0.46
CDY1; CDY1B Q9Y6F8 2/20 0.46
CDYL2 Q8N8U2 1/20 0.46
CDYL Q9Y232 1/20 0.46
KDM4E B2RXH2 2/20 0.45
LMNA P02545 2/20 0.45
HCRTR1 O43613 1/20 0.45
GAA P10253 2/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
TSHR P16473 2/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
CASP1 P29466 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28850424 1.00 ALDH1A1 (0.52) ALDH1A1MAPTPKMRAD52RAB9A
SCHEMBL28877344 0.87 ALDH1A1 (0.57) ALDH1A1MAPTPKMRAD52RAB9A
SCHEMBL30992147 0.85 ALDH1A1 (0.50) ALDH1A1MAPTPKMRAD52RAB9A
SCHEMBL31186392 0.84 ALDH1A1 (0.56) ALDH1A1MAPTPKMRAD52RAB9A
SCHEMBL30992133 0.84 RAD52 (0.51) ALDH1A1MAPTPKMRAD52RAB9A
SCHEMBL28496150 0.82 RAD52 (0.51) ALDH1A1MAPTPKMRAD52RAB9A
SCHEMBL28850362 0.82 CNR1 (0.51) ALDH1A1MAPTMAPK1LMNAMEN1
SCHEMBL28850360 0.82 CNR1 (0.51) ALDH1A1MAPTMAPK1LMNAMEN1
SCHEMBL31186320 0.82 ALDH1A1 (0.43) ALDH1A1MAPTPKMRAD52RAB9A
SCHEMBL3201165 0.81 ALDH1A1 (0.65) ALDH1A1MAPTPKMRAD52RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115141135-A Preparation method of oxindole-acetic acid compound containing 3-bit chiral quaternary carbon center 四川大学 2022-10-04 CN disclosed