Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28850360 | 1.00 | CNR1 (0.51) | CNR1GPR55ALDH1A1CYP2C19CYP1A2 | |
| SCHEMBL28877365 | 0.87 | USP2 (0.56) | CNR1GPR55ALDH1A1CYP2C19CYP1A2 | |
| SCHEMBL28850379 | 0.86 | ALDH1A1 (0.69) | ALDH1A1CYP2C19CYP3A4CYP2C9NPSR1 | |
| SCHEMBL28850377 | 0.86 | ALDH1A1 (0.69) | ALDH1A1CYP2C19CYP3A4CYP2C9NPSR1 | |
| SCHEMBL28850351 | 0.83 | ALDH1A1 (0.48) | ALDH1A1NPSR1MAPTTP53LMNA | |
| SCHEMBL28850352 | 0.83 | ALDH1A1 (0.48) | ALDH1A1NPSR1MAPTTP53LMNA | |
| SCHEMBL28850523 | 0.82 | ALDH1A1 (0.45) | ALDH1A1CYP2C19CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL28850524 | 0.82 | ALDH1A1 (0.45) | ALDH1A1CYP2C19CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL28850424 | 0.82 | ALDH1A1 (0.52) | ALDH1A1POLBUSP2MAPK1L3MBTL1 | |
| SCHEMBL28850422 | 0.82 | ALDH1A1 (0.52) | ALDH1A1POLBUSP2MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115141135-A | Preparation method of oxindole-acetic acid compound containing 3-bit chiral quaternary carbon center | 四川大学 | 2022-10-04 | — | — | CN | disclosed |