Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.52 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | GPR183 | P32249 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2379860 | 0.85 | MEN1 (0.66) | MEN1KMT2AMBTD1L3MBTL3ALDH1A1 | |
| SCHEMBL2378331 | 0.82 | MEN1 (0.70) | MEN1KMT2AMBTD1L3MBTL3ALDH1A1 | |
| SCHEMBL2379666 | 0.80 | POLB (0.65) | MEN1KMT2AMBTD1L3MBTL3POLB | |
| SCHEMBL3384758 | 0.78 | MBTD1 (0.68) | MEN1KMT2AMBTD1L3MBTL3ALDH1A1 | |
| SCHEMBL263317 | 0.78 | MBTD1 (0.73) | MEN1KMT2AMBTD1L3MBTL3ALDH1A1 | |
| SCHEMBL265068 | 0.76 | MBTD1 (0.71) | MEN1KMT2AMBTD1L3MBTL3ALDH1A1 | |
| SCHEMBL3391959 | 0.76 | MBTD1 (0.71) | MEN1KMT2AMBTD1L3MBTL3ALDH1A1 | |
| SCHEMBL31689628 | 0.76 | MBTD1 (0.71) | MEN1KMT2AMBTD1L3MBTL3ALDH1A1 | |
| SCHEMBL4005746 | 0.76 | GPR183 (0.60) | MEN1KMT2AMBTD1L3MBTL3ALDH1A1 | |
| SCHEMBL30754633 | 0.76 | GPR183 (0.57) | MEN1KMT2AMBTD1L3MBTL3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107148417-A | Benzo-aza * sulfonamide compounds | 豪夫迈·罗氏有限公司 | 2017-09-08 | — | — | CN | disclosed |