Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.68 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | IL1RN | P18510 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL263317 | 0.96 | MBTD1 (0.73) | MBTD1L3MBTL3ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL3391959 | 0.95 | MBTD1 (0.71) | MBTD1L3MBTL3ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL31689628 | 0.95 | MBTD1 (0.71) | MBTD1L3MBTL3ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL265068 | 0.95 | MBTD1 (0.71) | MBTD1L3MBTL3ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL3430555 | 0.89 | APOBEC3A (0.67) | MBTD1L3MBTL3ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL295085 | 0.86 | MBTD1 (0.61) | MBTD1L3MBTL3ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL100316 | 0.85 | ALDH1A1 (0.62) | MBTD1L3MBTL3ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL2379666 | 0.85 | POLB (0.65) | MBTD1L3MBTL3SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6798179 | 0.85 | MBTD1 (0.59) | MBTD1L3MBTL3ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL3387440 | 0.83 | MBTD1 (0.70) | MBTD1L3MBTL3ALDH1A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010052448-A2 | FUSED PYRAZINE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA S.A. (BE) | 2010-05-14 | — | — | WO | disclosed |