Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 2/20 | 0.41 |
| ▸ | NNMT | P40261 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 8/20 | 0.36 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.36 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.36 |
| ▸ | SIK1 | P57059 | 1/20 | 0.34 |
| ▸ | SIK2 | Q9H0K1 | 1/20 | 0.34 |
| ▸ | SIK3 | Q9Y2K2 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8524627 | 0.72 | NNMT (0.39) | IDH1NNMTPARP1PKN1PKN2 | |
| SCHEMBL19437531 | 0.72 | TLR8 (0.45) | IDH1NNMTPARP1PKN1PKN2 | |
| SCHEMBL11039311 | 0.72 | NNMT (0.52) | NNMTPARP1KDM4EIKBKBMAPT | |
| SCHEMBL23529352 | 0.68 | PKN1 (0.45) | PARP1PKN1PKN2 | |
| SCHEMBL14046288 | 0.68 | PARP1 (0.59) | NNMTPARP1KDM4EMAPTTDP1 | |
| SCHEMBL27556628 | 0.68 | NNMT (0.44) | NNMTPARP1KDM4EIKBKBMAPT | |
| SCHEMBL23552643 | 0.67 | PTGER4 (0.46) | PARP1PKN1PKN2 | |
| SCHEMBL23552540 | 0.67 | PKN1 (0.47) | IDH1PARP1PKN1PKN2 | |
| SCHEMBL25095012 | 0.67 | PKN1 (0.47) | PARP1PKN1PKN2 | |
| SCHEMBL23552645 | 0.67 | PTGER4 (0.45) | PARP1PKN1PKN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114981265-A | Compound (I) | CTXT私人有限公司 | 2022-08-30 | — | — | CN | disclosed |