Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 2/20 | 0.39 |
| ▸ | IDH1 | O75874 | 2/20 | 0.37 |
| ▸ | PARP1 | P09874 | 3/20 | 0.37 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | SIK1 | P57059 | 1/20 | 0.34 |
| ▸ | SIK2 | Q9H0K1 | 1/20 | 0.34 |
| ▸ | SIK3 | Q9Y2K2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30659665 | 0.73 | NQO2 (0.42) | HCAR3NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL11039311 | 0.73 | NNMT (0.52) | NNMTPARP1MAPTKDM4EALDH1A1 | |
| SCHEMBL28850690 | 0.72 | IDH1 (0.41) | NNMTIDH1PARP1MAPTKDM4E | |
| SCHEMBL304209 | 0.72 | NPC1 (0.40) | HCAR3NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL8953225 | 0.72 | KDM4E (0.38) | HCAR3NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL19437531 | 0.70 | TLR8 (0.45) | NNMTIDH1PARP1LMNAPKN1 | |
| SCHEMBL8952902 | 0.69 | HCAR3 (0.47) | HCAR3NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL13516493 | 0.69 | KDM4E (0.36) | IDH1SMN1; SMN2LMNAMAPTKDM4E | |
| SCHEMBL28443183 | 0.68 | KDM4E (0.35) | HCAR3NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL12970786 | 0.67 | NNMT (0.50) | NNMTPARP1SMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5932568-A | GASTROINTESTINAL DISORDERS | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1999-08-03 | — | — | US | disclosed |