Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 14/20 | 1.00 |
| ▸ | CYP1B1 | Q16678 | 14/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 13/20 | 1.00 |
| ▸ | PDE5A | O76074 | 5/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 1.00 |
| ▸ | NPC1 | O15118 | 2/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | TP53 | P04637 | 2/20 | 1.00 |
| ▸ | POLB | P06746 | 2/20 | 1.00 |
| ▸ | RAB9A | P51151 | 2/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | PKM | P14618 | 1/20 | 1.00 |
| ▸ | TSHR | P16473 | 1/20 | 1.00 |
| ▸ | PTGS1 | P23219 | 1/20 | 1.00 |
| ▸ | PTGS2 | P35354 | 1/20 | 1.00 |
| ▸ | THPO | P40225 | 1/20 | 1.00 |
| ▸ | MTOR | P42345 | 1/20 | 1.00 |
| ▸ | BLM | P54132 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Rutaecarpine SCHEMBL29693598 | 1.00 | CYP1A1 (1.00) | CYP1A1CYP1B1CYP1A2PDE5AKDM4E | |
| Rutaecarpine SCHEMBL29406533 | 1.00 | CYP1A1 (1.00) | CYP1A1CYP1B1CYP1A2PDE5AKDM4E | |
| SCHEMBL11047610 | 0.88 | CYP1A1 (0.78) | CYP1A1CYP1B1CYP1A2PDE5AKDM4E | |
| SCHEMBL25150530 | 0.88 | CYP1A1 (0.78) | CYP1A1CYP1B1CYP1A2PDE5AKDM4E | |
| SCHEMBL24753913 | 0.88 | CYP1A1 (0.78) | CYP1A1CYP1B1CYP1A2PDE5AKDM4E | |
| SCHEMBL5740905 | 0.88 | CYP1A1 (0.78) | CYP1A1CYP1B1CYP1A2PDE5AKDM4E | |
| SCHEMBL14297679 | 0.87 | CYP1A1 (1.00) | CYP1A1CYP1B1CYP1A2PDE5AKDM4E | |
| SCHEMBL11045375 | 0.87 | CYP1A1 (0.83) | CYP1A1CYP1B1CYP1A2PDE5AKDM4E | |
| SCHEMBL15500023 | 0.87 | CYP1A1 (0.76) | CYP1A1CYP1B1CYP1A2PDE5AKDM4E | |
| SCHEMBL11050683 | 0.87 | CYP1A1 (0.76) | CYP1A1CYP1B1CYP1A2PDE5AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1430 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4615506-A1 | USE OF GSK-3 ACTIVATIOR TO MODULATE PROTEASOME ACTIVITY TO PREVENT AGEING ASSOCIATED CONDITIONS AND DISEASES | Sahin, Fikret (TR) | 2025-09-17 | — | — | EP | claimed |
| CN-119930619-A | Rutaecarpine derivative with multi-target antitumor activity and application thereof | 中国人民解放军海军军医大学 | 2025-05-06 | — | — | CN | claimed |
| WO-2025076266-A1 | TOPICAL COMPOSITION | SIRENAS LLC (US) | 2025-04-10 | — | — | WO | claimed |
| CN-119770590-A | Child nerve soothing and distention eliminating foot membrane liquid containing Evodia rutaecarpa extract and preparation method thereof | 北京中联民康中医药研究院 | 2025-04-08 | — | — | CN | claimed |
| CN-119751457-A | Evodiamine derivative containing pyridine quaternary ammonium salt, preparation method and antibacterial application thereof | 南华大学 | 2025-04-04 | — | — | CN | claimed |
| CN-119587447-A | Evodia rutaecarpa soluble micro-needle for acupoint administration and preparation method and application thereof | 沈阳药科大学 | 2025-03-11 | — | — | CN | claimed |
| CN-119306720-A | Evodiamine derivative, rutaecarpine derivative, preparation method and application thereof | 济宁市第一人民医院(济宁市医学科学研究院) | 2025-01-14 | — | — | CN | claimed |
| CN-119291064-A | Method for constructing characteristic spectrum of Shuangjin stomach intestine capsule | 陕西科技大学 | 2025-01-10 | — | — | CN | claimed |
| WO-2024258363-A1 | USE OF GSK-3 ACTIVATIOR TO MODULATE PROTEASOME ACTIVITY TO PREVENT AGEING ASSOCIATED CONDITIONS AND DISEASES | SAHIN FIKRET (TR) | 2024-12-19 | — | — | WO | claimed |
| CN-118777450-A | Method for measuring content of multi-index components of erxiekang film | 上海儿童营养中心(海南)有限公司 | 2024-10-15 | — | — | CN | claimed |
| US-20060264497-A1 | Diindolylmethane-based compositions and methods of use thereof for promoting oral mucosal and bone health | BIORESPONSE, L.L.C. | 2006-11-23 | — | — | US | claimed |
| WO-2006105196-A2 | DIINDOLYLMETHANE-BASED COMPOSITIONS AND METHODS OF USE THEREOF FOR PROMOTING ORAL MUCOSAL AND BONE HEALTH | BIORESPONSE, L.L.C. (US) | 2006-10-05 | — | — | WO | claimed |
| WO-2006023377-A2 | BIOMIMETIC OF EVODIA RUTAECARPA FRUIT EXTRACT FOR AMELIORATION OF INFLAMMATION | APPLIED GENETICS INCORPORATED DERMATICS (US) | 2006-03-02 | — | — | WO | claimed |
| CN-1682807-A | Composition for treating gastropathy and its preparing method | ZHENGDA LUZHOU MED SCIENCE (CN) | 2005-10-19 | — | — | CN | claimed |
| CN-1682829-A | Wuji dripping pill for treating liver and stomach diseases and its preparing method | ZHENGDA LUZHOU MED SCIENCE (CN) | 2005-10-19 | — | — | CN | claimed |
| CN-1634641-A | Process for separating and purifying organic compound by macroporous absorption resin-reverse osmosis membrane | MENG YICHUN (CN) | 2005-07-06 | — | — | CN | claimed |
| CN-1568998-A | Blood pressure lowering medicine | LI YUANJIAN (CN) | 2005-01-26 | — | — | CN | claimed |
| CN-1312075-A | Lipid metabolism-improving agent | KYOWA HAKKO KOGYO KK (JP) | 2001-09-12 | — | — | CN | claimed |
| US-6214831-B1 | DECOMPOSING LIPIDS; ANTICHOLESTEROL AGENT | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2001-04-10 | — | — | US | claimed |
| US-4472399-A | Indolo[2',3';3,4]pyrido[2,1-b]quinazoline-5-ones, a process for the preparation thereof, and diuretic compositions and methods using them | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1984-09-18 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060264497-A1 | Diindolylmethane-based compositions and methods of use thereof for promoting oral mucosal and bone health | HPGDS, IDO1, IDO2 | CYP1A1 1817/4885CYP1B1 2321/4885CYP1A2 1465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.