Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | DHFR | P00374 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HEXA | P06865 | 1/20 | 0.41 |
| ▸ | HEXB | P07686 | 1/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28174452 | 0.88 | CTSD (0.48) | HPGDALDH1A1MAPTKDM4EHSD17B10 | |
| SCHEMBL31352914 | 0.87 | HPGD (0.45) | HPGDALDH1A1MAPTKDM4EHSD17B10 | |
| SCHEMBL1767757 | 0.75 | NPC1 (0.63) | ALDH1A1KDM4EGAADHFRADORA2A | |
| SCHEMBL18264130 | 0.70 | BTK (0.41) | HPGDALDH1A1KDM4EDHFRADORA2A | |
| SCHEMBL27749041 | 0.70 | CYP1A1 (0.48) | ALDH1A1MAPTKDM4EADORA2ARAB9A | |
| SCHEMBL28174449 | 0.70 | MAPT (0.41) | HPGDALDH1A1MAPTKDM4EHSD17B10 | |
| SCHEMBL28174450 | 0.70 | NPC1 (0.46) | HPGDALDH1A1MAPTKDM4EHSD17B10 | |
| SCHEMBL28042624 | 0.70 | ALDH1A1 (0.56) | HPGDALDH1A1MAPTKDM4EHSD17B10 | |
| SCHEMBL27969901 | 0.69 | MAPT (0.60) | HPGDALDH1A1MAPTKDM4EHSD17B10 | |
| SCHEMBL6087267 | 0.69 | ADORA2A (0.55) | HPGDALDH1A1MAPTKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107074896-A | Electroluminescent Imidazoquinoxaline Carbene Metal Complexes | UDC 爱尔兰有限责任公司 | 2017-08-18 | — | — | CN | disclosed |