Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | FYN | P06241 | 3/20 | 0.40 |
| ▸ | GRK5 | P34947 | 1/20 | 0.40 |
| ▸ | ALKBH5 | Q6P6C2 | 2/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23540645 | 0.88 | HDAC6 (0.48) | HDAC6KDM4EAPOBEC3ARAB9ASMN1; SMN2 | |
| SCHEMBL23540398 | 0.88 | HDAC6 (0.50) | HDAC6KDM4EAPOBEC3ARAB9ASMN1; SMN2 | |
| SCHEMBL23541010 | 0.85 | HDAC6 (0.41) | HDAC6KDM4EAPOBEC3ARAB9ASMN1; SMN2 | |
| SCHEMBL23541040 | 0.85 | HDAC6 (0.52) | HDAC6KDM4EAPOBEC3ARAB9ASMN1; SMN2 | |
| SCHEMBL7485602 | 0.83 | LMNA (0.57) | HDAC6KDM4EAPOBEC3ARAB9ASMN1; SMN2 | |
| SCHEMBL23540360 | 0.80 | HDAC6 (0.46) | HDAC6KDM4EAPOBEC3ARAB9ASMN1; SMN2 | |
| SCHEMBL23562539 | 0.77 | HDAC6 (0.54) | HDAC6KDM4EAPOBEC3ARAB9ASMN1; SMN2 | |
| SCHEMBL31747056 | 0.71 | BAZ2B (0.59) | RAB9ASMN1; SMN2HSD17B10LMNAFYN | |
| SCHEMBL23562856 | 0.70 | HDAC6 (0.51) | HDAC6KDM4EAPOBEC3ARAB9ASMN1; SMN2 | |
| SCHEMBL5070925 | 0.68 | KDM4E (0.49) | KDM4EAPOBEC3ARAB9ASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114980887-A | Fluoroalkyl-oxadiazoles and their use | 特纳亚治疗股份有限公司 | 2022-08-30 | — | — | CN | disclosed |