Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.32 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29584618 | 0.81 | ALDH1A1 (0.38) | ALDH1A1HPGDKDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL28851434 | 0.70 | L3MBTL1 (0.39) | ALDH1A1HPGDKDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL28851429 | 0.70 | L3MBTL1 (0.39) | ALDH1A1HPGDKDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL12165452 | 0.70 | SLC18A3 (0.39) | ALDH1A1HPGDL3MBTL1L3MBTL3KCNA5 | |
| SCHEMBL28377828 | 0.69 | POLB (0.31) | SMN1; SMN2SLC18A3 | |
| SCHEMBL12015481 | 0.68 | SLC18A3 (0.40) | ALDH1A1HPGDSMN1; SMN2L3MBTL1L3MBTL3 | |
| SCHEMBL28390615 | 0.66 | HRH3 (0.40) | L3MBTL1L3MBTL3AOC3 | |
| SCHEMBL12014347 | 0.65 | SLC18A3 (0.45) | ALDH1A1HPGDSMN1; SMN2SLC18A3TSHR | |
| SCHEMBL3516822 | 0.65 | ALDH1A1 (0.45) | ALDH1A1HPGDSMN1; SMN2L3MBTL1CRHBP | |
| SCHEMBL4975174 | 0.65 | ATM (0.41) | KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115109032-A | Quinoline derivative and application thereof in medicine | 成都百裕制药股份有限公司 | 2022-09-27 | — | — | CN | disclosed |