Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | PTGES | O14684 | 3/20 | 0.38 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23036810 | 0.80 | CNR2 (0.55) | ALDH1A1POLBNR3C1TSHRLMNA | |
| SCHEMBL425353 | 0.79 | ALDH1A1 (0.46) | ALDH1A1NPC1RAB9ANR3C2POLB | |
| SCHEMBL28852844 | 0.78 | NR1I2 (0.40) | NPC1MTORRAB9ACA2 | |
| SCHEMBL28389232 | 0.73 | NPC1 (0.48) | NPC1MTORRAB9ACA2MAPT | |
| SCHEMBL28902561 | 0.72 | CNR2 (0.49) | MEN1KMT2A | |
| SCHEMBL28491072 | 0.72 | CNR2 (0.49) | ALDH1A1NR3C1TSHRLMNAMAPT | |
| SCHEMBL10312253 | 0.70 | ALDH1A1 (0.64) | ALDH1A1POLBSMN1; SMN2CA2TSHR | |
| SCHEMBL2492170 | 0.70 | TSHR (0.53) | ALDH1A1NPC1RAB9ANR3C2POLB | |
| SCHEMBL14452194 | 0.70 | NPC1 (0.50) | ALDH1A1NPC1MTORRAB9ACA2 | |
| SCHEMBL2057187 | 0.69 | ALDH1A1 (0.54) | ALDH1A1NPC1RAB9APOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113200891-B | Preparation method of cis-N-styryl amide derivative | 华侨大学 | 2022-09-30 | — | — | CN | claimed |
| CN-113200891-A | Preparation method of cis-N-styryl amide derivative | 华侨大学 | 2021-08-03 | — | — | CN | claimed |
| CN-113200891-B | Preparation method of cis-N-styryl amide derivative | 华侨大学 | 2022-09-30 | — | — | CN | disclosed |
| CN-113200891-A | Preparation method of cis-N-styryl amide derivative | 华侨大学 | 2021-08-03 | — | — | CN | disclosed |