Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 7/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 7/20 | 0.38 |
| ▸ | RORC | P51449 | 3/20 | 0.36 |
| ▸ | RORA | P35398 | 1/20 | 0.36 |
| ▸ | RORB | Q92753 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28852909 | 0.78 | ALDH1A1 (0.42) | NPC1MTORRAB9ACA2 | |
| SCHEMBL28389232 | 0.71 | NPC1 (0.48) | NPC1MTORRAB9APTPN1NR1H2 | |
| SCHEMBL28852821 | 0.68 | NPC1 (0.42) | NPC1MTORRAB9APTPN1CA12 | |
| SCHEMBL28852773 | 0.66 | NPC1 (0.40) | NPC1MTORRAB9APTPN1NR1H2 | |
| SCHEMBL10699281 | 0.64 | APP (0.48) | NPC1MTORRAB9ANPSR1APP | |
| SCHEMBL28218124 | 0.64 | NR1I2 (0.56) | NR1I2NR1H2RORCRORARORB | |
| SCHEMBL28852744 | 0.64 | VCP (0.41) | NPC1MTORRAB9ANR1H2CA12 | |
| SCHEMBL28852810 | 0.64 | NPC1 (0.41) | NPC1MTORRAB9APTPN1CA12 | |
| Diphenylacetylene SCHEMBL27721387 | 0.63 | APP (0.60) | NPC1MTORRAB9ACA12CA1 | |
| SCHEMBL23036810 | 0.63 | CNR2 (0.55) | NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113200891-B | Preparation method of cis-N-styryl amide derivative | 华侨大学 | 2022-09-30 | — | — | CN | claimed |
| CN-113200891-A | Preparation method of cis-N-styryl amide derivative | 华侨大学 | 2021-08-03 | — | — | CN | claimed |
| CN-113200891-B | Preparation method of cis-N-styryl amide derivative | 华侨大学 | 2022-09-30 | — | — | CN | disclosed |
| CN-113200891-A | Preparation method of cis-N-styryl amide derivative | 华侨大学 | 2021-08-03 | — | — | CN | disclosed |