SCHEMBL28853012

SCHEMBL28853012

NC(=O)N(N)c1cc(C(=O)O)c(N(N)C(N)=O)c2ccccc12

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.37
HPGD P15428 2/20 0.37
CYP2C9 P11712 2/20 0.37
THRB P10828 1/20 0.37
TSHR P16473 1/20 0.37
ALOX12 P18054 1/20 0.37
ATIC P31939 1/20 0.37
KDM4E B2RXH2 4/20 0.36
LMNA P02545 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
PDE10A Q9Y233 1/20 0.36
NR4A1 P22736 1/20 0.36
NR4A2 P43354 1/20 0.36
NR4A3 Q92570 1/20 0.36
ALDH1A1 P00352 3/20 0.35
ALOX15 P16050 1/20 0.35
HTT P42858 2/20 0.35
MEN1 O00255 1/20 0.35
MAPT P10636 1/20 0.35
PKM P14618 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28094791 0.81 KEAP1 (0.34) KDM4ESMN1; SMN2ALDH1A1HTTMEN1
SCHEMBL27529944 0.75 KDM4E (0.34) HSD17B10HPGDCYP2C9THRBTSHR
SCHEMBL27896796 0.75 GAA (0.39) HSD17B10TSHRKDM4ELMNASMN1; SMN2
SCHEMBL27540348 0.75 TSHR (0.36) HSD17B10TSHRKDM4ELMNAALDH1A1
SCHEMBL27488337 0.75 KEAP1 (0.32)
SCHEMBL27879966 0.72 GAA (0.48) HSD17B10HPGDTSHRKDM4EALDH1A1
SCHEMBL28172033 0.69 TSHR (0.40) HSD17B10HPGDTSHRKDM4ELMNA
Ammonia Solution, Strong SCHEMBL27596380 0.69 ALDH1A1 (0.38) HSD17B10HPGDCYP2C9THRBTSHR
SCHEMBL28095080 0.69 GAA (0.40) TSHR
SCHEMBL28173153 0.69 GAA (0.45) HSD17B10HPGDTSHRKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107431207-A Binder resin for electrode of lithium secondary battery, electrode for lithium secondary battery, and lithium secondary battery 株式会社 PI 技术研究所 2017-12-01 CN disclosed