Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SAT1 | P21673 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28185095 | 0.80 | — | — | |
| SCHEMBL27904194 | 0.75 | PPARD (0.31) | TSHRPPARD | |
| SCHEMBL29715936 | 0.73 | PPARD (0.50) | PPARD | |
| SCHEMBL553419 | 0.72 | SAT1 (0.40) | SAT1CYP2C19MEN1GLAKMT2A | |
| SCHEMBL28462221 | 0.70 | AOX1 (0.33) | — | |
| SCHEMBL28470222 | 0.70 | PPARD (0.37) | PPARD | |
| SCHEMBL21461734 | 0.69 | TSHR (0.46) | TSHR | |
| SCHEMBL6666472 | 0.69 | — | — | |
| SCHEMBL28665434 | 0.69 | ALDH1A1 (0.36) | CYP1A2TSHR | |
| SCHEMBL15395698 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105367482-B | N acyl sulfonamides apoptosis accelerator | 阿斯利康(瑞典)有限公司 | 2017-12-12 | — | — | CN | disclosed |