Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29713890 | 0.83 | MAP4K4 (0.66) | MAP4K4EGFR | |
| SCHEMBL4692556 | 0.83 | MAP4K4 (0.66) | MAP4K4EGFR | |
| Water SCHEMBL28851833 | 0.82 | MAP4K4 (0.64) | MAP4K4EGFR | |
| Hydrochloric Acid SCHEMBL10969363 | 0.82 | MAP4K4 (0.64) | MAP4K4EGFR | |
| 4-Aminoquinazoline SCHEMBL29481714 | 0.81 | PI4KA (0.68) | MAP4K4 | |
| 4-Aminoquinazoline SCHEMBL5026560 | 0.81 | PI4KA (0.68) | MAP4K4 | |
| Trifluoroacetic Acid SCHEMBL29418884 | 0.78 | EGFR (0.43) | MAP4K4EGFR | |
| Trifluoroacetic Acid SCHEMBL31662344 | 0.78 | EGFR (0.43) | MAP4K4EGFR | |
| Toluene SCHEMBL27551696 | 0.75 | MAP4K4 (0.61) | MAP4K4EGFR | |
| SCHEMBL5027281 | 0.72 | MAP4K4 (0.54) | MAP4K4EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107556295-A | Quinazoline derivant and preparation method thereof | 正大天晴药业集团股份有限公司 | 2018-01-09 | — | — | CN | disclosed |
| CN-105555782-B | Quinazoline derivatives and process for their preparation | 正大天晴药业集团股份有限公司 | 2017-11-10 | — | — | CN | disclosed |