Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 11/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 5/20 | 0.43 |
| ▸ | PI4KA | P42356 | 1/20 | 0.41 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.41 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.41 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL29418884 | 1.00 | EGFR (0.43) | EGFRMAP4K4PI4KAPI4K2BPI4K2A | |
| SCHEMBL2847252 | 0.84 | MAP4K4 (0.56) | EGFRMAP4K4PI4KAPI4K2BPI4K2A | |
| SCHEMBL29418929 | 0.84 | MAP4K4 (0.56) | EGFRMAP4K4PI4KAPI4K2BPI4K2A | |
| Trifluoroacetic Acid SCHEMBL3567636 | 0.81 | NCF1 (0.42) | EGFRMAP4K4CDK5CDK5R1SLC22A12 | |
| 4-Aminoquinazoline SCHEMBL29481714 | 0.80 | PI4KA (0.68) | MAP4K4PI4KAPI4K2BPI4K2API4KB | |
| 4-Aminoquinazoline SCHEMBL5026560 | 0.80 | PI4KA (0.68) | MAP4K4PI4KAPI4K2BPI4K2API4KB | |
| Trifluoroacetic Acid SCHEMBL28853097 | 0.78 | MAP4K4 (0.52) | EGFRMAP4K4 | |
| Trifluoroacetic Acid SCHEMBL3567635 | 0.75 | L3MBTL1 (0.54) | MAP4K4CDK5SLC22A12 | |
| Trifluoroacetic Acid SCHEMBL29977443 | 0.75 | EGFR (0.43) | EGFRCDK5CDK5R1SLC22A12 | |
| Trifluoroacetic Acid SCHEMBL30391689 | 0.75 | EGFR (0.43) | EGFRCDK5CDK5R1SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151594-A1 | FUSED AZINES AS RAS INHIBITORS AND METHODS OF USE THEREOF | KESTREL THERAPEUTICS INC. (US) | 2025-07-17 | — | — | WO | disclosed |