Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 5/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.47 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | ATIC | P31939 | 1/20 | 0.44 |
| ▸ | HNF4A | P41235 | 1/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28068404 | 0.84 | KDM4E (0.48) | HSD17B10HPGDTSHRTHRBCYP2C9 | |
| SCHEMBL9651394 | 0.77 | PTPN1 (0.69) | PTPN1AKR1C2AKR1C1AKR1C3PTPN6 | |
| SCHEMBL28006571 | 0.76 | HSD17B10 (0.67) | PTPN1AKR1C2AKR1C1AKR1C3PTPN6 | |
| SCHEMBL2790332 | 0.76 | HSD17B10 (0.57) | PTPN1AKR1C2AKR1C1AKR1C3PTPN6 | |
| SCHEMBL28184150 | 0.72 | PTPN1 (0.57) | PTPN1AKR1C2AKR1C1AKR1C3PTPN6 | |
| SCHEMBL24868762 | 0.71 | LDHA (0.54) | PTPN1AKR1C2AKR1C1AKR1C3PTPN6 | |
| SCHEMBL6842109 | 0.71 | PTPN1 (0.70) | PTPN1AKR1C2AKR1C1AKR1C3PTPN6 | |
| SCHEMBL9618861 | 0.70 | HSD17B10 (0.74) | PTPN1AKR1C2AKR1C1AKR1C3PTPN6 | |
| SCHEMBL10343413 | 0.70 | HSD17B10 (0.67) | HSD17B10HPGDTSHRTHRBCYP2C9 | |
| SCHEMBL27785281 | 0.69 | HSD17B10 (0.55) | AKR1C2AKR1C1HSD17B10HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105566110-B | A kind of synthetic method of polysubstituted 1 naphthols and its derivative | 南开大学 | 2017-10-20 | — | — | CN | disclosed |