Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.44 |
| ▸ | RELA | Q04206 | 2/20 | 0.44 |
| ▸ | CCR6 | P51684 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28853099 | 0.84 | PTPN1 (0.49) | KDM4EMAPK1ALDH1A1HPGDTSHR | |
| SCHEMBL28333209 | 0.84 | KDM4E (0.57) | KDM4EMAPK1L3MBTL1TDP1ALDH1A1 | |
| SCHEMBL27933355 | 0.83 | CCR6 (0.53) | KDM4EMAPK1L3MBTL1TDP1ALDH1A1 | |
| SCHEMBL28335553 | 0.82 | MAPK1 (0.56) | KDM4EMAPK1L3MBTL1TDP1ALDH1A1 | |
| SCHEMBL28068265 | 0.80 | ALDH1A1 (0.50) | KDM4EMAPK1L3MBTL1TDP1ALDH1A1 | |
| SCHEMBL27933324 | 0.80 | CCR6 (0.48) | KDM4EMAPK1L3MBTL1TDP1ALDH1A1 | |
| SCHEMBL28879263 | 0.77 | ERN1 (0.47) | KDM4ETDP1ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL4830396 | 0.77 | TSHR (0.63) | KDM4EMAPK1L3MBTL1TDP1ALDH1A1 | |
| SCHEMBL28335530 | 0.77 | ERN1 (0.51) | KDM4EMAPK1L3MBTL1TDP1ALDH1A1 | |
| SCHEMBL28335604 | 0.76 | ALDH1A1 (0.50) | KDM4EMAPK1L3MBTL1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105566110-B | A kind of synthetic method of polysubstituted 1 naphthols and its derivative | 南开大学 | 2017-10-20 | — | — | CN | disclosed |
| CN-105566110-A | Synthesis method of polysubstituted 1-naphthol and derivatives thereof | UNIV NANKAI | 2016-05-11 | — | — | CN | disclosed |