Phenol

Phenol

SCHEMBL2885488

CC(C)=O.Cc1cccc(O)c1C.Oc1ccccc1

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 3/20 0.65
ATM Q13315 1/20 0.65
HSD17B10 Q99714 4/20 0.46
LMNA P02545 3/20 0.46
TP53 P04637 2/20 0.46
HTT P42858 2/20 0.46
NPC1 O15118 1/20 0.46
TSHR P16473 1/20 0.46
RAB9A P51151 1/20 0.46
CYP1A2 P05177 2/20 0.46
CYP2C19 P33261 1/20 0.46
ESR1 P03372 1/20 0.44
ESR2 Q92731 1/20 0.44
TDP1 Q9NUW8 2/20 0.42
CA12 O43570 2/20 0.42
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
CA9 Q16790 2/20 0.42
CA14 Q9ULX7 2/20 0.42
GLA P06280 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL11792275 0.92 TRPA1 (0.77) TRPA1ATMHSD17B10LMNATP53
Phenol SCHEMBL1471734 0.92 TRPA1 (0.77) TRPA1ATMHSD17B10LMNATP53
Phenol SCHEMBL6131043 0.90 TRPA1 (0.68) TRPA1ATMHSD17B10LMNATP53
Orthocresol SCHEMBL11213183 0.88 TRPA1 (0.71) TRPA1ATMHSD17B10LMNATP53
Orthocresol SCHEMBL11678278 0.88 TRPA1 (0.71) TRPA1ATMHSD17B10LMNATP53
Orthocresol SCHEMBL11030781 0.88 TRPA1 (0.71) TRPA1ATMHSD17B10LMNATP53
Orthocresol SCHEMBL11679129 0.88 TRPA1 (0.71) TRPA1ATMHSD17B10LMNATP53
Acetic Acid SCHEMBL28437480 0.88 TRPA1 (0.77) TRPA1ATMHSD17B10LMNATP53
Phenol SCHEMBL27682271 0.86 TRPA1 (0.68) TRPA1ATMHSD17B10LMNATP53
Bicarbonate SCHEMBL27605791 0.86 TRPA1 (0.81) TRPA1ATMHSD17B10LMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2142585-A1 BRANCHED POLYCARBONATE RESINS AND PROCESSES TO PREPARE THE SAME Sabic Innovative Plastics IP B.V. (NL) 2010-01-13 EP claimed
WO-2008051652-A1 BRANCHED POLYCARBONATE RESINS AND PROCESSES TO PREPARE THE SAME SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-05-02 WO claimed
US-20080004426-A1 Branched Polycarbonate Resins and Processes to Prepare the Same GENERAL ELECTRIC COMPANY (US) 2008-01-03 US claimed
US-7759456-B2 Branched polycarbonate resins and processes to prepare the same SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-07-20 US disclosed
EP-2142585-A1 BRANCHED POLYCARBONATE RESINS AND PROCESSES TO PREPARE THE SAME Sabic Innovative Plastics IP B.V. (NL) 2010-01-13 EP disclosed
WO-2008051652-A1 BRANCHED POLYCARBONATE RESINS AND PROCESSES TO PREPARE THE SAME SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-05-02 WO disclosed
US-20080004426-A1 Branched Polycarbonate Resins and Processes to Prepare the Same GENERAL ELECTRIC COMPANY (US) 2008-01-03 US disclosed