Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15218262 | 0.81 | PTGDR2 (0.36) | PDE4APDE4BPDE4CPDE4DPDCD1 | |
| SCHEMBL293625 | 0.81 | GAA (0.56) | PDE4APDE4BPDE4CPDE4DGAA | |
| SCHEMBL5549042 | 0.81 | ALOX15 (0.47) | PDE4APDE4BPDE4CPDE4DGAA | |
| SCHEMBL15814604 | 0.80 | PTGDR2 (0.37) | PDE4APDE4BPDE4CPDE4DALOX12 | |
| SCHEMBL14236162 | 0.79 | PDE4A (0.46) | PDE4APDE4BPDE4CPDE4DGAA | |
| SCHEMBL1317039 | 0.79 | PDE4A (0.46) | PDE4APDE4BPDE4CPDE4DGAA | |
| SCHEMBL15525407 | 0.79 | NQO2 (0.47) | ERN1ALOX15ALOX12MEN1KMT2A | |
| SCHEMBL9817534 | 0.76 | PDE4A (0.50) | PDE4APDE4BPDE4CPDE4DPDCD1 | |
| SCHEMBL23783141 | 0.75 | ERN1 (0.44) | PDE4APDE4BPDE4CPDE4DGAA | |
| SCHEMBL10600312 | 0.75 | MAPT (0.50) | PDE4APDE4BPDE4CPDE4DGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115151538-A | Macrocyclic compounds, process for their preparation and pharmaceutical compositions containing them | 法国施维雅药厂 | 2022-10-04 | — | — | CN | disclosed |