Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | SHBG | P04278 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12535526 | 0.88 | CYP3A4 (0.39) | PTGDR2SHBGSLC6A2SLC6A4PDCD1 | |
| SCHEMBL28855400 | 0.86 | MAPT (0.33) | PTGDR2SHBGSLC6A2SLC6A4PDCD1 | |
| SCHEMBL24012991 | 0.84 | HDAC1 (0.34) | PTGDR2SHBGSLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL27002534 | 0.84 | PTGDR2 (0.32) | PTGDR2SHBGSLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL28855352 | 0.81 | PDE4A (0.47) | PTGDR2PDCD1CD274PDE4APDE4B | |
| SCHEMBL1229960 | 0.80 | NOTUM (0.33) | — | |
| SCHEMBL13584746 | 0.79 | SHBG (0.35) | SHBGPDCD1CD274ALDH1A1PDE4A | |
| SCHEMBL6123894 | 0.78 | ACHE (0.41) | SHBGPDCD1CD274ALDH1A1PDE4A | |
| SCHEMBL9999575 | 0.78 | PDCD1 (0.41) | SHBGPDCD1CD274ALDH1A1MAPT | |
| SCHEMBL15814604 | 0.77 | PTGDR2 (0.37) | PTGDR2ALDH1A1LMNAMAPTPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2451875-B1 | VISIBLE LIGHT ABSORBERS FOR OPHTHALMIC LENS MATERIALS | NOVARTIS AG (CH) | 2013-08-28 | — | — | EP | disclosed |