Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 13/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 13/20 | 0.41 |
| ▸ | F11 | P03951 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17418864 | 1.00 | LPL (0.41) | LPLLIPGF11CSF1RROCK1 | |
| SCHEMBL30159194 | 1.00 | LPL (0.41) | LPLLIPGF11CSF1RROCK1 | |
| SCHEMBL17419172 | 0.87 | LPL (0.42) | LPLLIPGF11CA1CA2 | |
| SCHEMBL28855364 | 0.83 | LPL (0.40) | LPLLIPGF11CA1CA2 | |
| SCHEMBL21364646 | 0.83 | LPL (0.46) | LPLLIPGF11ROCK1CA1 | |
| SCHEMBL28855361 | 0.83 | LPL (0.40) | LPLLIPGF11CA1CA2 | |
| SCHEMBL28855507 | 0.80 | CSF1R (0.44) | LPLLIPGF11CSF1RCA1 | |
| SCHEMBL28855580 | 0.80 | CSF1R (0.44) | LPLLIPGF11CSF1RCA1 | |
| SCHEMBL28855673 | 0.80 | CSF1R (0.44) | LPLLIPGF11CSF1RCA1 | |
| SCHEMBL2699826 | 0.79 | PDE2A (0.44) | LPLLIPGF11CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4110776-A1 | NEW MACROCYCLIC COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Les Laboratoires Servier (FR) | 2023-01-04 | — | — | EP | disclosed |
| CN-115151538-A | Macrocyclic compounds, process for their preparation and pharmaceutical compositions containing them | 法国施维雅药厂 | 2022-10-04 | — | — | CN | disclosed |