Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 1/20 | 0.44 |
| ▸ | LPL | P06858 | 9/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 9/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
| ▸ | F11 | P03951 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28855507 | 1.00 | CSF1R (0.44) | CSF1RLPLLIPGAAK1ADRA2A | |
| SCHEMBL28855580 | 1.00 | CSF1R (0.44) | CSF1RLPLLIPGAAK1ADRA2A | |
| SCHEMBL24478331 | 0.88 | CSF1R (0.46) | CSF1RLPLLIPGAAK1CA1 | |
| SCHEMBL27159911 | 0.83 | CSF1R (0.43) | CSF1RLPLLIPGAAK1CA1 | |
| SCHEMBL30159194 | 0.80 | LPL (0.41) | CSF1RLPLLIPGCA1CA2 | |
| SCHEMBL28855475 | 0.80 | LPL (0.41) | CSF1RLPLLIPGCA1CA2 | |
| SCHEMBL17418864 | 0.80 | LPL (0.41) | CSF1RLPLLIPGCA1CA2 | |
| SCHEMBL25203373 | 0.79 | CSF1R (0.48) | CSF1RLPLLIPGCA1CA2 | |
| SCHEMBL1877988 | 0.79 | CSF1R (0.48) | CSF1RLPLLIPGCA1CA2 | |
| SCHEMBL28855364 | 0.79 | LPL (0.40) | LPLLIPGAAK1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4110776-A1 | NEW MACROCYCLIC COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Les Laboratoires Servier (FR) | 2023-01-04 | — | — | EP | disclosed |
| CN-115151538-A | Macrocyclic compounds, process for their preparation and pharmaceutical compositions containing them | 法国施维雅药厂 | 2022-10-04 | — | — | CN | disclosed |