Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.49 |
| ▸ | NAPRT | Q6XQN6 | 3/20 | 0.42 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
| ▸ | WNT3A | P56704 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 4/20 | 0.38 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.36 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.36 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM5A | P29375 | 2/20 | 0.36 |
| ▸ | KDM3A | Q9Y4C1 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL11881380 | 0.90 | P2RX7 (0.53) | P2RX7NAPRTP4HTMLMNAL3MBTL1 | |
| SCHEMBL29587616 | 0.88 | — | — | |
| SCHEMBL37469 | 0.88 | — | — | |
| SCHEMBL27705986 | 0.86 | P2RX7 (0.57) | P2RX7NAPRTP4HTMLMNAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL28466502 | 0.86 | P2RX7 (0.57) | P2RX7NAPRTP4HTMLMNAL3MBTL1 | |
| SCHEMBL27474788 | 0.86 | P2RX7 (0.57) | P2RX7NAPRTP4HTMLMNAL3MBTL1 | |
| Bromide SCHEMBL10349040 | 0.86 | P2RX7 (0.57) | P2RX7NAPRTP4HTMLMNAL3MBTL1 | |
| SCHEMBL31022254 | 0.86 | P2RX7 (0.57) | P2RX7NAPRTP4HTMLMNAL3MBTL1 | |
| SCHEMBL29062401 | 0.86 | P2RX7 (0.57) | P2RX7NAPRTP4HTMLMNAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL1224737 | 0.86 | P2RX7 (0.57) | P2RX7NAPRTP4HTMLMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107646035-A | Heterocyclyl methyl thieno uracil as adenosine A 2B receptor antagonists | 拜耳制药股份公司 | 2018-01-30 | — | — | CN | disclosed |