Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 6/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 6/20 | 0.39 |
| ▸ | SIRT3 | Q9NTG7 | 6/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.36 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28855777 | 0.87 | MAPT (0.48) | RAB9AMAPTALDH1A1NPC1PKM | |
| SCHEMBL31336843 | 0.80 | NPC1 (0.49) | RAB9AMAPTALDH1A1NPC1PKM | |
| SCHEMBL23580027 | 0.80 | NPC1 (0.49) | RAB9AMAPTALDH1A1NPC1PKM | |
| SCHEMBL28855745 | 0.79 | HTR2C (0.55) | RAB9ANPC1LMNASIRT2SIRT1 | |
| SCHEMBL30034195 | 0.74 | CNR1 (0.47) | RAB9AMAPTALDH1A1NPC1PKM | |
| SCHEMBL23579593 | 0.74 | CNR1 (0.47) | RAB9AMAPTALDH1A1NPC1PKM | |
| SCHEMBL29230284 | 0.73 | STAT3 (0.61) | RAB9AMAPTNPC1PKMLMNA | |
| SCHEMBL2476480 | 0.72 | PKM (0.55) | RAB9AMAPTALDH1A1NPC1PKM | |
| SCHEMBL29230268 | 0.70 | LMNA (0.59) | LMNA | |
| SCHEMBL29036011 | 0.69 | AKT2 (0.64) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115151550-A | Ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP 1) modulators and uses thereof | 桑福德·伯纳姆·普雷比医学发现研究所 | 2022-10-04 | — | — | CN | disclosed |