Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 19/20 | 0.64 |
| ▸ | JAK1 | P23458 | 3/20 | 0.64 |
| ▸ | BTK | Q06187 | 2/20 | 0.64 |
| ▸ | TEC | P42680 | 1/20 | 0.64 |
| ▸ | TXK | P42681 | 1/20 | 0.64 |
| ▸ | BLK | P51451 | 1/20 | 0.64 |
| ▸ | BMX | P51813 | 1/20 | 0.64 |
| ▸ | ITK | Q08881 | 1/20 | 0.64 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28855720 | 0.84 | JAK3 (0.59) | JAK3JAK1BTKTECTXK | |
| SCHEMBL24867427 | 0.84 | JAK3 (0.77) | JAK3JAK1BTKTECTXK | |
| SCHEMBL21333438 | 0.82 | JAK3 (0.66) | JAK3JAK1BTKTECTXK | |
| SCHEMBL23221794 | 0.82 | JAK3 (0.66) | JAK3JAK1BTKTECTXK | |
| SCHEMBL26095750 | 0.82 | JAK3 (0.77) | JAK3JAK1BTKTECTXK | |
| SCHEMBL23619474 | 0.81 | JAK3 (0.56) | JAK3JAK1BTKTECTXK | |
| SCHEMBL28855733 | 0.81 | JAK3 (0.73) | JAK3JAK1BTKTECTXK | |
| SCHEMBL23408959 | 0.80 | JAK3 (0.65) | JAK3JAK1BTKTECTXK | |
| SCHEMBL22909510 | 0.80 | JAK3 (0.65) | JAK3JAK1BTKTECTXK | |
| SCHEMBL23408967 | 0.80 | JAK3 (0.65) | JAK3JAK1BTKTECTXK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115023221-B | Stable immediate release tablet and capsule formulations of 1- ((2 s,5 r) -5- ((7H-pyrrolo [2,3-D ] pyrimidin-4-yl) amino) -2-methylpiperidin-1-yl) prop-2-en-1-one | 辉瑞英国研发有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-115023221-A | Stable immediate release tablet and capsule formulations of 1- ((2S,5R) -5- ((7H-pyrrolo [2,3-D ] pyrimidin-4-yl) amino) -2-methylpiperidin-1-yl) prop-2-en-1-one | 辉瑞英国研发有限公司 | 2022-09-06 | — | — | CN | disclosed |