Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 5/20 | 0.79 |
| ▸ | CA2 | P00918 | 4/20 | 0.79 |
| ▸ | CA1 | P00915 | 3/20 | 0.79 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.49 |
| ▸ | TUBB | P07437 | 1/20 | 0.49 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.49 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.49 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.49 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.49 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.49 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.49 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.49 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.49 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.49 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.49 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.49 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.49 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4673 | 0.89 | CA2 (1.00) | ENPP2CA2CA1TUBB4ATUBB | |
| SCHEMBL28331836 | 0.87 | CA2 (0.95) | ENPP2CA2CA1TUBB4ATUBB | |
| SCHEMBL5836185 | 0.83 | CA2 (0.86) | ENPP2CA2CA1TUBB4ATUBB | |
| SCHEMBL28832985 | 0.83 | CA2 (0.86) | ENPP2CA2CA1TUBB4ATUBB | |
| SCHEMBL257917 | 0.83 | CA2 (0.86) | ENPP2CA2CA1TUBB4ATUBB | |
| Acetonitrile SCHEMBL28133848 | 0.81 | ENPP2 (0.82) | ENPP2CA2CA1CA7CA9 | |
| Magnesium Chloride Anhydrous SCHEMBL20694971 | 0.81 | ENPP2 (0.83) | ENPP2CA2CA1TUBB4ATUBB | |
| SCHEMBL16179596 | 0.79 | CA2 (0.79) | ENPP2CA2CA1TUBB4ATUBB | |
| SCHEMBL14247630 | 0.79 | CA2 (0.79) | ENPP2CA2CA1TUBB4ATUBB | |
| SCHEMBL10047630 | 0.78 | CA2 (0.76) | ENPP2CA2CA1TUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107531683-A | USP7 INHIBITOR COMPOUNDS AND METHODS OF USE | 豪夫迈·罗氏有限公司 | 2018-01-02 | — | — | CN | disclosed |