Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | AGXT | P21549 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL920894 | 0.88 | CETP (0.42) | TSHRIDO1CETPTP53AGXT | |
| SCHEMBL562799 | 0.86 | CETP (0.45) | TSHRCETPALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL10736052 | 0.85 | CETP (0.47) | CETPTP53MAPK1 | |
| SCHEMBL8338694 | 0.85 | CETP (0.47) | CETPTP53MAPK1 | |
| SCHEMBL10731438 | 0.85 | CETP (0.47) | CETPTP53MAPK1 | |
| SCHEMBL10733438 | 0.85 | CETP (0.47) | CETPTP53MAPK1 | |
| SCHEMBL287942 | 0.83 | TSHR (0.48) | TSHRIDO1TP53AGXTALDH1A1 | |
| SCHEMBL6506525 | 0.80 | IDO1 (0.43) | TSHRIDO1CETPTP53AGXT | |
| SCHEMBL10887507 | 0.80 | IDO1 (0.45) | IDO1AGXTALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL10887896 | 0.79 | IDO1 (0.50) | TSHRIDO1TP53AGXTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117320706-A | Aminothiol ester compounds or derivatives thereof as immunomodulators | 高级生物设计公司 | 2023-12-29 | — | — | CN | claimed |
| US-20230250066-A1 | HERBICIDAL CINNOLINE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2023-08-10 | — | — | US | claimed |
| EP-4153573-A1 | HERBICIDAL CINNOLINE DERIVATIVES | Syngenta Crop Protection AG (CH) | 2023-03-29 | — | — | EP | claimed |
| CN-115697975-A | Herbicidal cinnoline derivatives | 先正达农作物保护股份公司 | 2023-02-03 | — | — | CN | claimed |
| CN-114341110-A | Aminothiol ester compound and use thereof | 高级生物设计公司 | 2022-04-12 | — | — | CN | claimed |
| WO-2021233787-A1 | HERBICIDAL CINNOLINE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2021-11-25 | — | — | WO | claimed |
| EP-3833657-A1 | AMINOTHIOLESTER COMPOUNDS AND USES THEREOF | Advanced Biodesign (FR) | 2021-06-16 | — | — | EP | claimed |
| WO-2021019071-A1 | AMINOTHIOLESTER COMPOUNDS AND USES THEREOF | ADVANCED BIODESIGN (FR) | 2021-02-04 | — | — | WO | claimed |
| EP-0777646-B1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARM (GB) | 2001-09-05 | — | — | EP | claimed |
| EP-0821666-B1 | DERIVATIVES OF SUCCINAMIDE AND THEIR USE AS METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARM (GB) | 2000-12-27 | — | — | EP | claimed |
| EP-0821668-B1 | DERIVATIVES OF SUCCINAMIDE AND THEIR USE AS METALLOPROTEINASE INHIBITOR | BRITISH BIOTECH PHARM (GB) | 2000-08-23 | — | — | EP | claimed |
| US-5908851-A | TUMOR NECROSIS FACTOR, COLLAGENASE, STROMELYSIN, AND GELATINASE INHIBITORS; OSTEOPOROSIS, RHEUMATIC AND ORAL DISEASES; ANTIARTHRITIC AND ANTIULCER AGENTS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1999-06-01 | — | — | US | claimed |
| US-5840939-A | Derivatives of succinamide and their use as metalloproteinase inhibitors | BRITISH BIOTECH PHARMACEUTICALS, LTD. (GB) | 1998-11-24 | — | — | US | claimed |
| US-5763621-A | Metalloproteinase inhibitors | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1998-06-09 | — | — | US | claimed |
| EP-0821668-A1 | DERIVATIVES OF SUCCINAMIDE AND THEIR USE AS METALLOPROTEINASE INHIBITOR | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1998-02-04 | — | — | EP | claimed |
| EP-0821666-A1 | DERIVATIVES OF SUCCINAMIDE AND THEIR USE AS METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1998-02-04 | — | — | EP | claimed |
| EP-0777646-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1997-06-11 | — | — | EP | claimed |
| WO-1996033165-A1 | DERIVATIVES OF SUCCINAMIDE AND THEIR USE AS METALLOPROTEINASE INHIBITOR | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1996-10-24 | — | — | WO | claimed |
| WO-1996033161-A1 | DERIVATIVES OF SUCCINAMIDE AND THEIR USE AS METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1996-10-24 | — | — | WO | claimed |
| WO-1996006074-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1996-02-29 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230250066-A1 | HERBICIDAL CINNOLINE DERIVATIVES | DDT, CYP1B1, DERL1 | TSHR 3874/4885IDO1 260/4885CETP 4467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.