Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.48 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | RHEB | Q15382 | 1/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1253598 | 0.84 | ALDH1A1 (0.59) | ALDH1A1IMPDH2HSD11B1ASH1LKDM4E | |
| SCHEMBL29948415 | 0.84 | ALDH1A1 (0.59) | ALDH1A1IMPDH2HSD11B1ASH1LKDM4E | |
| SCHEMBL7376923 | 0.74 | HSD11B1 (0.67) | ALDH1A1HSD11B1ASH1LKDM4EMAPT | |
| SCHEMBL31175932 | 0.72 | KMT2A (0.71) | ALDH1A1IMPDH2MEN1LMNATHRB | |
| SCHEMBL249552 | 0.72 | KMT2A (0.71) | ALDH1A1IMPDH2MEN1LMNATHRB | |
| SCHEMBL31091904 | 0.71 | ALDH1A1 (0.40) | ALDH1A1IMPDH2KDM4EPTPN1MEN1 | |
| SCHEMBL13720529 | 0.70 | ALDH1A1 (0.44) | ALDH1A1IMPDH2HSD11B1ASH1LKDM4E | |
| SCHEMBL31588841 | 0.70 | KMT2A (0.67) | ALDH1A1IMPDH2KDM4EMAPTMEN1 | |
| SCHEMBL27511393 | 0.70 | KMT2A (0.67) | ALDH1A1IMPDH2KDM4EMAPTMEN1 | |
| SCHEMBL31177892 | 0.70 | MEN1 (0.48) | ALDH1A1KDM4EMAPTPTPN1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115181090-B | New application of indoline 3,4 naphthaline ring skeleton compound and plant bactericide | 青岛农业大学 | 2023-04-14 | — | — | CN | disclosed |
| CN-115093395-B | Indoline 3, 4-naphthaline ring framework compound, preparation method and application thereof | 青岛农业大学 | 2023-03-28 | — | — | CN | disclosed |
| CN-115181090-A | New application of indoline 3, 4-naphthaline ring framework compound and plant bactericide | 青岛农业大学 | 2022-10-14 | — | — | CN | disclosed |
| CN-115093395-A | Indoline 3, 4-naphthalene ring framework compound, preparation method and application thereof | 青岛农业大学 | 2022-09-23 | — | — | CN | disclosed |