Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 10/20 | 0.42 |
| ▸ | CA2 | P00918 | 10/20 | 0.42 |
| ▸ | CA9 | Q16790 | 8/20 | 0.42 |
| ▸ | CA12 | O43570 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28856497 | 0.93 | ALDH1A1 (0.45) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL28856480 | 0.91 | CA1 (0.43) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL28856511 | 0.79 | CA1 (0.35) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL28856479 | 0.76 | MAPT (0.34) | ALDH1A1TSHRMAPK1MAPTPKM | |
| SCHEMBL14885478 | 0.76 | CA1 (0.42) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL16010092 | 0.76 | CA1 (0.42) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL25964293 | 0.76 | CA1 (0.42) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL14882300 | 0.76 | CA1 (0.42) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL28856544 | 0.76 | MAPT (0.34) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL28856483 | 0.74 | SMN1; SMN2 (0.34) | CA1CA2CA9CA12ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109608432-B | Thiophene derivatives as URAT1 inhibitors | 江苏艾立康医药科技有限公司 | 2022-10-11 | — | — | CN | disclosed |