Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 6/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | PRNP | P04156 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28856483 | 0.94 | SMN1; SMN2 (0.34) | SLC22A12SMN1; SMN2ALDH1A1MAPK1RXFP1 | |
| SCHEMBL28954999 | 0.91 | SLC22A12 (0.34) | SLC22A12SMN1; SMN2ALDH1A1MAPK1RXFP1 | |
| SCHEMBL28856503 | 0.87 | MAPK1 (0.34) | SLC22A12SMN1; SMN2ALDH1A1MAPK1RXFP1 | |
| SCHEMBL28856565 | 0.86 | SLC22A12 (0.41) | SLC22A12SMN1; SMN2ALDH1A1RXFP1MEN1 | |
| SCHEMBL28856557 | 0.85 | SLC22A12 (0.34) | SLC22A12SMN1; SMN2ALDH1A1MAPK1MEN1 | |
| SCHEMBL28856484 | 0.83 | MAPT (0.40) | TP53GAANPSR1MAPTKDM4E | |
| SCHEMBL28856533 | 0.82 | SLC22A12 (0.36) | SLC22A12ALDH1A1KDM4EHPGD | |
| SCHEMBL28856501 | 0.82 | SLC22A12 (0.35) | SLC22A12SMN1; SMN2ALDH1A1MAPK1RXFP1 | |
| SCHEMBL28856490 | 0.81 | SLC22A12 (0.40) | SLC22A12SMN1; SMN2RXFP1MEN1KMT2A | |
| SCHEMBL28856505 | 0.81 | ALDH1A1 (0.35) | SMN1; SMN2ALDH1A1MAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109608432-B | Thiophene derivatives as URAT1 inhibitors | 江苏艾立康医药科技有限公司 | 2022-10-11 | — | — | CN | disclosed |