Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 3/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 8/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | NMT2 | O60551 | 1/20 | 0.34 |
| ▸ | NMT1 | P30419 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28856557 | 0.92 | SLC22A12 (0.34) | MAPTTP53POLBCDK9CCNT1 | |
| SCHEMBL28856483 | 0.90 | SMN1; SMN2 (0.34) | MAPTTP53KDM4EGAAATM | |
| SCHEMBL28856533 | 0.89 | SLC22A12 (0.36) | CDK9CCNT1KDM4E | |
| SCHEMBL28856505 | 0.87 | ALDH1A1 (0.35) | TP53POLBKDM4ENPSR1L3MBTL1 | |
| SCHEMBL28856477 | 0.87 | SLC22A12 (0.35) | CDK9IDO1KDM4EATM | |
| SCHEMBL28856507 | 0.86 | SLC22A12 (0.39) | IDO1 | |
| SCHEMBL28954999 | 0.84 | SLC22A12 (0.34) | MAPTTP53KDM4EGAANPSR1 | |
| SCHEMBL28856503 | 0.84 | MAPK1 (0.34) | MAPTTP53CDK9CCNT1KDM4E | |
| SCHEMBL28856485 | 0.83 | SLC22A12 (0.35) | MAPTTP53KDM4EGAAATM | |
| SCHEMBL28856508 | 0.80 | SLC22A12 (0.39) | MAPTTP53KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109608432-B | Thiophene derivatives as URAT1 inhibitors | 江苏艾立康医药科技有限公司 | 2022-10-11 | — | — | CN | disclosed |