Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | PPOX | P50336 | 4/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28856520 | 0.77 | SLC22A12 (0.39) | PPARAPPOXSLC22A12TP53POLB | |
| SCHEMBL3284462 | 0.74 | ALDH1A1 (0.46) | PPARASLC22A12TP53MMP8CYP1A2 | |
| SCHEMBL28856519 | 0.73 | SLC22A12 (0.38) | PPARAPPOXSLC22A12TP53POLB | |
| SCHEMBL31284515 | 0.73 | PIN1 (0.40) | PPARAPOLBMMP8CYP1A2TSHR | |
| SCHEMBL15038070 | 0.73 | HDAC4 (0.41) | POLBMMP8CYP1A2TSHRALDH1A1 | |
| SCHEMBL28856529 | 0.72 | TP53 (0.33) | PPARAPPOXSLC22A12TP53POLB | |
| SCHEMBL9994877 | 0.72 | PIN1 (0.45) | PPARAPPOXSLC22A12TP53POLB | |
| SCHEMBL737377 | 0.71 | SMN1; SMN2 (0.49) | PPOXSLC22A12TP53CYP1A2TSHR | |
| SCHEMBL1464689 | 0.70 | PIN1 (0.50) | PPARATP53POLBMMP8CYP1A2 | |
| SCHEMBL1465616 | 0.70 | ALDH1A1 (0.46) | PPARATP53POLBMMP8CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109608432-B | Thiophene derivatives as URAT1 inhibitors | 江苏艾立康医药科技有限公司 | 2022-10-11 | — | — | CN | disclosed |