Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 6/20 | 0.48 |
| ▸ | SLC22A12 | Q96S37 | 11/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29896812 | 1.00 | PPARA (0.48) | PPARASLC22A12MEN1KMT2ARXFP1 | |
| SCHEMBL28856481 | 0.91 | PPARA (0.48) | PPARASLC22A12MEN1KMT2ARXFP1 | |
| SCHEMBL28856510 | 0.88 | PPARA (0.43) | PPARASLC22A12 | |
| SCHEMBL29896814 | 0.88 | PPARA (0.43) | PPARASLC22A12 | |
| SCHEMBL28856562 | 0.87 | PPARA (0.42) | PPARASLC22A12 | |
| SCHEMBL29896818 | 0.87 | PPARA (0.42) | PPARASLC22A12 | |
| SCHEMBL29896802 | 0.86 | SMN1; SMN2 (0.37) | PPARASLC22A12MEN1KMT2ARXFP1 | |
| SCHEMBL28856550 | 0.86 | SMN1; SMN2 (0.37) | PPARASLC22A12MEN1KMT2ARXFP1 | |
| SCHEMBL29896734 | 0.84 | PPARA (0.48) | PPARASLC22A12 | |
| SCHEMBL28856531 | 0.84 | SLC22A12 (0.58) | PPARASLC22A12NPC1TP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109608432-B | Thiophene derivatives as URAT1 inhibitors | 江苏艾立康医药科技有限公司 | 2022-10-11 | — | — | CN | disclosed |