Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 8/20 | 0.48 |
| ▸ | SLC22A12 | Q96S37 | 9/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28856532 | 0.91 | PPARA (0.48) | PPARASLC22A12MEN1NPC1KMT2A | |
| SCHEMBL29896812 | 0.91 | PPARA (0.48) | PPARASLC22A12MEN1NPC1KMT2A | |
| SCHEMBL28856545 | 0.86 | PPOX (0.37) | PPARASLC22A12MEN1NPC1KMT2A | |
| SCHEMBL28856531 | 0.84 | SLC22A12 (0.58) | PPARASLC22A12NPC1 | |
| SCHEMBL29896814 | 0.81 | PPARA (0.43) | PPARASLC22A12 | |
| SCHEMBL28856510 | 0.81 | PPARA (0.43) | PPARASLC22A12 | |
| SCHEMBL28856562 | 0.80 | PPARA (0.42) | PPARASLC22A12 | |
| SCHEMBL29896818 | 0.80 | PPARA (0.42) | PPARASLC22A12 | |
| SCHEMBL28856534 | 0.78 | PPARA (0.48) | PPARASLC22A12 | |
| SCHEMBL29896734 | 0.78 | PPARA (0.48) | PPARASLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109608432-B | Thiophene derivatives as URAT1 inhibitors | 江苏艾立康医药科技有限公司 | 2022-10-11 | — | — | CN | disclosed |