Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PPOX | P50336 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | PRNP | P04156 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29896802 | 1.00 | SMN1; SMN2 (0.37) | SMN1; SMN2ALDH1A1PPOXMAPK1RXFP1 | |
| SCHEMBL28856545 | 0.92 | PPOX (0.37) | SMN1; SMN2ALDH1A1PPOXMAPK1RXFP1 | |
| SCHEMBL29896764 | 0.90 | ALDH1A1 (0.36) | SMN1; SMN2ALDH1A1PPOXMAPK1MEN1 | |
| SCHEMBL28856556 | 0.90 | ALDH1A1 (0.36) | SMN1; SMN2ALDH1A1PPOXMAPK1MEN1 | |
| SCHEMBL29896755 | 0.89 | AAK1 (0.39) | PPOXMEN1KMT2APPARA | |
| SCHEMBL28856498 | 0.89 | AAK1 (0.39) | PPOXMEN1KMT2APPARA | |
| SCHEMBL28856515 | 0.86 | SLC22A12 (0.43) | ALDH1A1TP53PRNPSLC22A12 | |
| SCHEMBL29896717 | 0.86 | SLC22A12 (0.36) | PPOXSLC22A12PPARAATM | |
| SCHEMBL29896812 | 0.86 | PPARA (0.48) | SMN1; SMN2RXFP1MEN1KMT2ATP53 | |
| SCHEMBL28856532 | 0.86 | PPARA (0.48) | SMN1; SMN2RXFP1MEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109608432-B | Thiophene derivatives as URAT1 inhibitors | 江苏艾立康医药科技有限公司 | 2022-10-11 | — | — | CN | disclosed |