Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ERN1 | O75460 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | PHGDH | O43175 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1662914 | 0.85 | GAA (0.59) | SMN1; SMN2GAAERN1ALDH1A1TP53 | |
| SCHEMBL29486100 | 0.79 | GAA (0.52) | SMN1; SMN2GAAKDM4EERN1ALDH1A1 | |
| SCHEMBL28746378 | 0.79 | GAA (0.52) | SMN1; SMN2GAAKDM4EERN1ALDH1A1 | |
| SCHEMBL15265342 | 0.77 | KDM4E (0.65) | SMN1; SMN2GAAKDM4EERN1ALDH1A1 | |
| SCHEMBL18299399 | 0.77 | ERN1 (0.58) | SMN1; SMN2KDM4EERN1TSHRMAPT | |
| SCHEMBL7121916 | 0.76 | SMN1; SMN2 (0.77) | SMN1; SMN2GAAALDH1A1TP53TSHR | |
| (2-Chlorophenyl)(Morpholino)Methanone SCHEMBL6938284 | 0.75 | MGLL (0.68) | SMN1; SMN2GAAKDM4EALDH1A1TSHR | |
| SCHEMBL855339 | 0.74 | POLB (0.60) | SMN1; SMN2GAAKDM4EALDH1A1TSHR | |
| SCHEMBL28941346 | 0.74 | MAPT (0.54) | SMN1; SMN2GAAKDM4ETSHRMAPT | |
| SCHEMBL30073359 | 0.74 | POLB (0.60) | SMN1; SMN2GAAKDM4EALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107820494-A | Nuclear receptor modulators | 艾伯维公司 | 2018-03-20 | — | — | CN | disclosed |