Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PHGDH | O43175 | 1/20 | 0.50 |
| ▸ | ERN1 | O75460 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28746378 | 1.00 | GAA (0.52) | GAASMN1; SMN2KDM4EALDH1A1TP53 | |
| SCHEMBL20516441 | 0.86 | HPGD (0.56) | GAASMN1; SMN2KDM4EALDH1A1MAPT | |
| SCHEMBL20516437 | 0.84 | HPGD (0.58) | GAASMN1; SMN2KDM4EALDH1A1MAPT | |
| SCHEMBL1663182 | 0.84 | ALDH1A1 (0.67) | GAASMN1; SMN2ALDH1A1TP53MAPT | |
| SCHEMBL31661720 | 0.84 | ALDH1A1 (0.67) | GAASMN1; SMN2ALDH1A1TP53MAPT | |
| SCHEMBL2375485 | 0.82 | ALDH1A1 (0.55) | GAASMN1; SMN2ALDH1A1TP53MAPT | |
| SCHEMBL2376795 | 0.82 | HPGD (0.53) | GAASMN1; SMN2ALDH1A1TP53MAPT | |
| SCHEMBL28856992 | 0.79 | SMN1; SMN2 (0.50) | GAASMN1; SMN2KDM4EALDH1A1TP53 | |
| SCHEMBL7121916 | 0.78 | SMN1; SMN2 (0.77) | GAASMN1; SMN2ALDH1A1TP53KMT2A | |
| (2-Chlorophenyl)(Morpholino)Methanone SCHEMBL6938284 | 0.78 | MGLL (0.68) | GAASMN1; SMN2KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114423741-B | aryl-N-aryl derivatives for the treatment of RNA viral infections | ABIVAX公司 | 2023-11-07 | — | — | CN | disclosed |
| CN-114423741-A | aryl-N-aryl derivatives for the treatment of RNA viral infections | ABIVAX公司 | 2022-04-29 | — | — | CN | disclosed |