Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.35 |
| ▸ | TEK | Q02763 | 1/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29601011 | 1.00 | CHRNB2 (0.39) | CHRNB2CHRNB4CHRNA3CHRNA4GAA | |
| SCHEMBL28054466 | 0.89 | CHRNB2 (0.39) | CHRNB2CHRNB4CHRNA3CHRNA4GAA | |
| SCHEMBL30789010 | 0.89 | CHRNB2 (0.39) | CHRNB2CHRNB4CHRNA3CHRNA4GAA | |
| SCHEMBL28269615 | 0.89 | CHRNB2 (0.41) | CHRNB2CHRNB4CHRNA3CHRNA4GAA | |
| SCHEMBL30620798 | 0.89 | CHRNB2 (0.41) | CHRNB2CHRNB4CHRNA3CHRNA4GAA | |
| SCHEMBL29601544 | 0.89 | CHRNB2 (0.39) | CHRNB2CHRNB4CHRNA3CHRNA4GAA | |
| SCHEMBL29140304 | 0.89 | CHRNB2 (0.39) | CHRNB2CHRNB4CHRNA3CHRNA4GAA | |
| SCHEMBL29601512 | 0.87 | CYP11B1 (0.39) | CHRNB2CHRNB4CHRNA3CHRNA4GAA | |
| SCHEMBL28857181 | 0.87 | CYP11B1 (0.39) | CHRNB2CHRNB4CHRNA3CHRNA4GAA | |
| Vonoprazan SCHEMBL194487 | 0.86 | GAA (0.40) | CHRNB2CHRNB4CHRNA3CHRNA4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117417323-A | Method for preparing voronoi and salt thereof | 爱斯特（成都）生物制药股份有限公司 | 2024-01-19 | — | — | CN | disclosed |
| CN-114149412-A | Intermediate compound for preparing Vonoprazan | 鲁南制药集团股份有限公司 | 2022-03-08 | — | — | CN | disclosed |